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Index > Protein center > Cyp2d4(Gene name) > Rat
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  • Cyp2d4 (Gene name),
  • Cytochrome P450 2D4 (Protein name ),  CP2D4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyp2d4(Cyp2d-4);
    Protein name:
    Cytochrome P450 2D4;
    Alternative:
    Cytochrome P450-CMF3;CYPIID4;Debrisoquine 4-hydroxylase;Cytochrome P450-DB4;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    500
    Sequence:
    50:
    MRMPTGSELW | PIAIFTIIFL | LLVDLMHRRQ | RWTSRYPPGP | VPWPVLGNLL | 
    100:
    QIDFQNMPAG | FQKLRCRFGD | LFSLQLAFES | VVVLNGLPAL | REALVKYSED | 
    150:
    TADRPPLHFN | DQSGFGPRSQ | GVVLARYGPA | WRQQRRFSVS | TFRHFGLGKK | 
    200:
    SLEQWVTEEA | RCLCAAFADH | SGFPFSPNTL | LDKAVCNVIA | SLLFACRFEY | 
    250:
    NDPRFIRLLD | LLKDTLEEES | GFLPMLLNVF | PMLLHIPGLL | GKVFSGKKAF | 
    300:
    VAMLDELLTE | HKVTWDPAQP | PRDLTDAFLA | EVEKAKGNPE | SSFNDENLRV | 
    350:
    VVADLFMAGM | VTTSTTLTWA | LLFMILHPDV | QCRVQQEIDE | VIGQVRRPEM | 
    400:
    ADQARMPFTN | AVIHEVQRFA | DILPLGVPHK | TSRDIEVQGF | LIPKGTTLIT | 
    450:
    NLSSVLKDET | VWEKPLRFHP | EHFLDAQGNF | VKHEAFMPFS | AGRRACLGEP | 
    500:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 2D4
    Cat.:
    E8849r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Cytochrome P450 2D4
    Cat.:
    U8849r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Rat Cytochrome P450 2D4
    Cat.:
    P8849Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Cytochrome P450 2D4
    Protein for Rat Cytochrome P450 2D4

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site."
      Matsunaga E. , Umeno M. , Gonzalez F.J.
      J. Mol. Evol.30:155-169(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity."
      Wan J. , Imaoka S. , Chow T. , Hiroi T. , Yabusaki Y. , Funae Y.
      Arch. Biochem. Biophys.348:383-390(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Sprague-Dawley.
      tissue: Brain.
    3. 3.
      "Four species of cDNAs for cytochrome P450 isozymes immunorelated to P450C-M/F encode for members of P450IID subfamily, increasing the number of members within the subfamily."
      Ishida N. , Tawaragi Y. , Inuzuka C. , Sugita O. , Kubota I. , Nakazato H. , Noguchi T. , Sassa S.
      Biochem. Biophys. Res. Commun.156:681-688(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 177-500
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